Characterization of Three O-Methyltransferases Involved in Noscapine Biosynthesis in Opium Poppy
نویسندگان
چکیده
منابع مشابه
Characterization of three O-methyltransferases involved in noscapine biosynthesis in opium poppy.
Noscapine is a benzylisoquinoline alkaloid produced in opium poppy (Papaver somniferum) and other members of the Papaveraceae. It has been used as a cough suppressant and more recently was shown to possess anticancer activity. However, the biosynthesis of noscapine in opium poppy has not been established. A proposed pathway leading from (S)-reticuline to noscapine includes (S)-scoulerine, (S)-c...
متن کاملCharacterization of Three O-Methyltransferases Involved in Noscapine Biosynthesis in Opium Poppy1[W]
Noscapine is a benzylisoquinoline alkaloid produced in opium poppy (Papaver somniferum) and other members of the Papaveraceae. It has been used as a cough suppressant and more recently was shown to possess anticancer activity. However, the biosynthesis of noscapine in opium poppy has not been established. A proposed pathway leading from (S)-reticuline to noscapine includes (S)scoulerine, (S)-ca...
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O-Methyltransferases, which catalyze the production of small molecules in plants, play a crucial role in determining biosynthetic pathways in secondary metabolism because of their strict substrate specificity. Using three O-methyltransferase (OMT) cDNAs that are involved in berberine biosynthesis, we investigated the structure that was essential for this substrate specificity and the possibilit...
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ژورنال
عنوان ژورنال: Plant Physiology
سال: 2012
ISSN: 1532-2548
DOI: 10.1104/pp.112.194886